Disease Information: Dengue Fever is a mosquito-born virus that is a member of the Flaviviride virus family. The virus can result in symptoms such as fever, chills, nausea, rashes, and joint pain. It is most common in areas with a high density population and is only spread by infected mosquitos. It is also one of the most common arthropod born diseases.
Do Not Need this info for Spring (but still copy these lines to your Target page for now) Primer design results for pNIC-Bsa4 cloning (list seqeunces of all of your ~40 nt long primers):(link to DNA Works output text file - that should be saved in your Google Docs folder after you did the primer design protocol) -- Ask a mentor, Dr. B, or a fellow researcher -how to link a GDocs file if you are not sure how to.
E.C. Number: 2.1.1.57
PDB ID: 1L9K
Organism: Dengue Virus type 2 (strain Puerto Rico)
Ethiological Risk Group: n/a
Disease Information: Dengue Fever is a mosquito-born virus that is a member of the Flaviviride virus family. The virus can result in symptoms such as fever, chills, nausea, rashes, and joint pain. It is most common in areas with a high density population and is only spread by infected mosquitos. It is also one of the most common arthropod born diseases.
Dengue Overview
embopress.org
Essentiallity:
The target is essential for the synthesis of RNA and invest themselves in the replication machinery of the virus.
Essentiality
Brenda
Link
ExPasy
Structure:
TMPred page:
Expasy TMpred
Gene Sequence:
>fig|243365.4.peg.112|CV_0121|VBIChrVio67196_0112| SSU rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase (EC 2.1.1.182) [Chromobacterium violaceum ATCC 12472 | 243365.4]
atgagcaagcacatcccgcgcaagcgtttcgggcagaacttcctgcaggacgccagcgtc
atcgccggcatcgtccacgcggtcaatccgcagcctgacgacatcgtcatcgagatcggc
cccgggctgggcgccatcaccaagccgttgctggcgcgcctcaagcatctgcacgtggtg
gagatcgaccgcgacatcatcgagcggctcaaggccgaacatccggccgacaagctgacc
atccacgccggcgacgcgctggccttcgacttcgcctcggtcagcgaggcgccgctgaag
atcgtcggcaacctgccgtacaatatctccacgccgctgctgttccacctggccagctac
ggcaaccgggtgacggacatgcatttcatgctgcagaaggaagtgatagagcgcatggtg
gccgagccgtccaccgccgattacggccggctgacagtgatgctgcagtaccgtttctac
atggaaaacatcctgttcgtgccgccggaggcgttctggccgccgccgaaggtggattcc
gccgtggtgcggatgattccggcgccgggccgctgcggcaccgcgcgcgatgaggcgctg
ctggagaagctggtgagccaggcgttcgcccagcgccgcaagacgctgcgcaacaacctg
aagggcctggccgacgcggccgacctggaggcgctgggcatcgaccccggcctgcgtccg
gaaaacctgccggtggaggatttcgtccgcctggccaaccatctgcacgacaagggcgcg
cgcggctga
Protein Sequence:
>fig|243365.4.peg.112|CV_0121|VBIChrVio67196_0112| SSU rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase (EC 2.1.1.182) [Chromobacterium violaceum ATCC 12472 | 243365.4]
MSKHIPRKRFGQNFLQDASVIAGIVHAVNPQPDDIVIEIGPGLGAITKPLLARLKHLHVV
EIDRDIIERLKAEHPADKLTIHAGDALAFDFASVSEAPLKIVGNLPYNISTPLLFHLASY
GNRVTDMHFMLQKEVIERMVAEPSTADYGRLTVMLQYRFYMENILFVPPEAFWPPPKVDS
AVVRMIPAPGRCGTARDEALLEKLVSQAFAQRRKTLRNNLKGLADAADLEALGIDPGLRP
ENLPVEDFVRLANHLHDKGARG
Do Not Need this info for Spring (but still copy these lines to your Target page for now)
Primer design results for pNIC-Bsa4 cloning (list seqeunces of all of your ~40 nt long primers):(link to DNA Works output text file -
that should be saved in your Google Docs folder after you did the primer design protocol)
-- Ask a mentor, Dr. B, or a fellow researcher -how to link a GDocs file if you are not sure how to.